unknown
A faster version of pedigree programs of Linkage
Genetic linkage analysis is a statistical technique used to map
genes and find the approximate location of disease genes. There
was a standard software package for genetic linkage called
LINKAGE. FASTLINK is a significantly modified and improved
version of the main programs of LINKAGE that runs much faster
sequentially, can run in parallel, allows the user to recover
gracefully from a computer crash, and provides abundant new
documentation. FASTLINK has been used in over 1000 published
genetic linkage studies.
This package contains the following programs:
ilink: GEMINI optimization procedure to find a locally
optimal value of the theta vector of recombination
fractions
linkmap: calculates location scores of one locus against a
fixed map of other loci
lodscore: compares likelihoods at locally optimal theta
mlink: calculates lod scores and risk with two of more loci
unknown: identify possible genotypes for unknowns
- Homepage
- http://www.ncbi.nlm.nih.gov/CBBResearch/Schaffer/fastlink.html
- Package
- fastlink | source